| Subtopic | Posts | Updated | Creator | |
|
| San Pedro (Trichocereus pachanoi) & T. peruvians | 148 | 7/03 | |
|
| Cactus Links Page | 1 | ||
|
| Peyote | 66 | 7/03 | |
|
| San Pedro, Peyote, Mescaline (imported web site) | 7 | 7/03 | clearwhitelight.org |
|
| List of Active Cacti | 1 | ||
|
| Grandfather Peyote | 1 | 7/03 | cannabisculture.com |
|
| Mescaline Extractions | 29 | 7/03 | |
|
| Cactus Biology | 9 | 9/03 | Fungusmaximus |
|
| Pharmahuasca: On Phenethylamines and Potentiation | 1 | 7/03 | MAPS.org |
|
| Cactus Care: Precautions Against Pests and Diseases | 5 | 4/04 | Fungusmaximus |
| By ShrooMaster (Shroomaster) on Tuesday, December 25, 2001 - 12:40 am: |
mescaline
chemical name: 3,4,5-trimethoxybenethylmine
alternate names: 3,4,5-trimeoxyphenethylamine: mezcaline
chemical formula: C11H17NO3
molecular weight: 211.26
melting point: 35-36 C bp 180
LD50: crystals 212 mg/kg i.p. [mice]
LD50: 132 mg/kg {rats} crystals
LD50: crystals 326 mg/kg i.p. {guinea pigs]
3-methoxytyramine
quantity: %1-10 T.Pachanoi alkaloids
Lophophora diffusa contains NO mescaline according to Hans-Jorg Helmin and Rudolph Brenneisen Journal Of Chromatography, 593 [1992] 87-94. evident by a trip report folowing this info L. Diffusa is very active but not a mescaline trip. said to be more delirious like belladonna or datura [OH SHIT]. why did i bother to mention this, after all im only ordering williamsii anyway? well from what i read it would take a pro to tell the difference between the williamsii and the diffusa, and i cant claim to be one of those. just another reason to make sure your vendor knows his shit.
http://leda.lyceaum.org/chemicals/mescaline.12.shtml contains a large list of mescaline containing cacti, for those who are curious. im looking for a few other things so i may post more...
| Posted by: Nanook Nov 22 02, 02:17 PM GMT |
| Many thanks to Zilla for the research: MESCALINE: PEYOTE SAN PEDRO CACTUS SHAMANIC SACRAMENTS INTENSITY: 3 to 8 for most experiences. MATERIAL: Mescaline is a naturally occurring psychedelic found in several cactus species, most notably, Peyote (Lophophora williamsii) and San Pedro (Trichocereus pachanoi). Several other members of the trichocereus family also contain mescaline. Mescaline belongs to a family of compounds known as phenethylamines, making it quite distinct from the other major psychedelics which belong to the indole family. LSD, psilocybin, harmaline, and DMT are all indoles. Many synthetic "designer" psychedelics, such as ecstasy (MDMA) and 2C-B, are phenethylamines, and are related to the chemistry of mescaline. In addition to containing mescaline, the cacti mentioned above contain a large variety of related psychoactive compounds, and will produce experiences that are qualitatively different than pure mescaline. The experience produced by Peyote is also quite distinct from that produced by cacti from the trichocereus family. The literature I've read indicates that many members of the trichocereus family are psychoactive. I've only tried three or four of these and found them to be basically equal in potency. Many references indicate that one variety, Trichocereus peruvianus, is several times as potent by weight as the other trichocereus species. Psychoactive species include: |
SIDE EFFECT AND DANGERS
Several studies have been done by different investigators on the effects of
Peyote consumption on human chromosomes. One study of the Huichol Indians found
no abnormalities, even though the subjects took Peyote an average of 35 times a
year all through their adult lives. Another study of the Yanomama Indians of
Venezuela found no detectable incidence of chromosomal damage of either sex,
despite the fact that only the men partook in Peyote.
A study of Navaho members of the Native American Church who used Peyote
regularly, drew some interesting conclusions. The study was based on a sample
group of about 30,000 participants in the Peyote ritual. For the purpose of the
survey, it was assumed that each participant partook once a month. ( This is a
low approximation ) Of an estimated 180,000 ingestions, there were only 5
reported incidences of negative reactions.
This works out to about one bad trip in 70,000. Even though this studies figures
are probably somewhat off, it is obvious that the incidence of negative
reactions to mescaline are very low. It should be noted that the ingestions took
place in a more or less structured and controlled environment. The chances of a
bad reaction in stressful settings is probably greater. Anxiety is almost a
universal side effect for the inexperienced user. It is not being caused
directly by the mescaline, but by your apprehension of taking it.
Possible negative side effects that may be encountered, and frequency of
occurrence are:
Anxiety - Very common
Queasiness or upset stomach - Very common
Nausea - Common
Muscle tension (tightening of muscle in neck and face) - Common
Respiratory pressure (hard to breath) - Uncommon
Feeling of lose of control - Common at higher doses ( Ego dissolution )
Feeling of fear - Common with inexperienced users
HAZARDS AND WARNINGS
I have not been able to find any LD-50 information on mescaline and man. However
if you are a large Rat, then it is strongly advised not to exceed 370 mg / kg
body weight of mescaline. The highest known dose given to a human was 1500 mg .
( LD50 = Dosage that will kill half of a control group that take it ).
WARNING: Certain prescription drugs such as insulin, barbiturates or
physostigmine, are known to increase the toxicity of mescaline. It is possible
that the presence of hyperinsulinism, in conjunction with a large dose of
mescaline could prove fatal. Be very careful mixing insulin and mescaline.
WARNING: Mescaline should not be taken by pregnant women. Several animal studies
have reported birth defects, miscarriage, and possibly behavioral problems. Of
important note, fetal brain levels of mescaline have been found to be 2 - 4
times higher than the mother. There is a possibility that the use of mescaline
during pregnancy could be harmful to the fetus, although no human studies have
been done. I might mention that very common substances like alcohol or even
caffeine can cause fetal birth defects.
There are conflicting views on whether mescaline is dangerous to use with MAO
inhibitors. There have been several reports of the use of a strong, but short
lasting and reversible MAOI in conjunction with mescaline. Harmala compounds in
significant dosages were used to potentiate mescaline with no apparent side
effects. Caution is advised whenever using MAOI's.
Overdoses of mescaline are very rare, but if necessary can be treated
effectively in an Emergency Room by the administration of a phenothiazine
tranquilizer. This should be a measure of only last resort. Do not try to
medicate yourself, people in panic attacks tend to overreact, and try to
administer too much.
Bad trips and the feeling that you are dying are not totally unheard of, but
just remember that it is all in your mind, and you will come down eventually.
There have been NO recorded instances of someone dying because of ingesting
mescaline.
There has been widespread rumors that taking hallucinogens could set off
schizophrenic attacks in susceptible individuals, this idea has since been
generally dismissed. It is important to note that diagnosed schizophrenics are
comfortably able to ingest Peyote. This suggests that psychedelics do not in
themselves trigger psychotic episodes, but may allow some sort of stress
releasing mechanism to emerge.
Copyright (c) 1996, 1997, Klaus Trenary